Cardiac involvement in newborn of diabetic mothers

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Involvement of microRNA-133 and -29 in cardiac disturbances in diabetic ovariectomized rats

Objective(s): Menopause and diabetes obviously increase the risk of cardiovascular disease in women. The aims of the present study were to evaluate the effects of ovariectomy in type 2 diabetes on the histology and expression of miRNA-29, miRNA-133, IGF-1 and Bcl-2 genes and Bcl-2 protein and caspase 3 activity in the hearts of female rats. Materials and Methods: Forty Female Wistar rats were ...

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involvement of microrna-133 and -29 in cardiac disturbances in diabetic ovariectomized rats

objective(s): menopause and diabetes obviously increase the risk of cardiovascular disease in women. the aims of the present study were to evaluate the effects of ovariectomy in type 2 diabetes on the histology and expression of mirna-29, mirna-133, igf-1 and bcl-2 genes and bcl-2 protein and caspase 3 activity in the hearts of female rats. materials and methods: forty female wistar rats were d...

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Infants of diabetic mothers.

9 Grodsky, G. M., and Forsham, P. H.: An immunochemical assay of total extractable insulin in man. J. Clin. Invest. 39:1070, i960. 10 Field, J. B., and Woodson, M. L.: Studies on the circulating insulin inhibitor found in some diabetic patients exhibiting chronic insulin resistance. J. Clin. Invest. 38:551, 1959. 11 Mitchell, M. L.: Interaction of radioinsulin with serum proteins in vitro and w...

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Infants of diabetic mothers.

1024 These infants are remarkable not only because, like foetal versions of Shadrach, Meshach and Abednego, they emerge at least alive from within the fiery metabolic furnace of diabetes mellitus, but because they resemble one another so closely that they might well be related. They are plump, sleek, liberally coated with vemix caseosa, fullfaced and plethoric. The umbilical cord and tile place...

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Infants of diabetic mothers.

Advances in the management of the mother with diabetes have reduced the rate of morbidity and mortality for her infant. Aggressive control of maternal glycemic status is warranted, because most morbidities are epidemiologically and pathophysiologically closely linked to fetal hyperglycemia and hyperinsulinemia. The burgeoning public health problem of overweight and obesity in children will like...

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ژورنال

عنوان ژورنال: Archives of Cardiovascular Diseases Supplements

سال: 2020

ISSN: 1878-6480

DOI: 10.1016/j.acvdsp.2019.09.358